高旭

流行病學；衰老；精準環境健康🚚；腦健康；老年健康；

1. 國家自然科學基金（82304098）：基於SLC25A51基因甲基化動態調控研究黑碳損傷老年人認知功能的作用機製🧘🏿‍♂️。2024.1 – 2026.12 主持

2. 廣西環境暴露組學與全生命周期健康重點實驗室開放課題（2023-GKLEH-03）👯‍♀️：老年人環境重金屬暴露與生物學年齡的長壽隊列研究。2023.10-2025.09 主持

3. 中國疾病預防控製中心環境與人群健康重點實驗室開放基金（2022-CKL-03）🕵🏻‍♀️：鎘與砷慢性暴露對老年人虛弱狀態的影響及 DNA 甲基化機製研究🙎🏽‍♂️。 2022.01-2023.12 主持

4. 國家重點研發計劃（2023YFC3603400）：我國長壽人群的生命健康要素和延緩衰老靶標研究🙍🏽‍♂️。2023.12-2026.11 子課題負責人

5. 國家重點研發計劃（2022YFC3702704）👩🏻‍🌾：中國居民對大氣汙染響應的全生命過程健康效應譜研究♊️。2022.10-2026.03 項目骨幹

6. 美國NIH R01 基金 （R01ES025225）: Circulating microRNAs in Extracellular Vesicles, Air Particulate Pollution, and Lung Function in an Aging Cohort. 2018 – 2020 參與

7. 美國NIH R01 基金 （R01ES027747）: Air Particulate, Metals, and Cognitive Performance in an Aging Cohort – Roles of Circulating Extracellular Vesicles and Non-coding RNAs. 2018 – 2020 參與

8. 意大利嘉利堡基金會Fondazione Cariplo老齡化疾病研究專項（2017-0653）🌷：The Trithorax and Polycomb group proteins UTX and EzH2 in the Frailty Syndrome. 2017-2020 參與

1. Wang Y#, Li H#, Huang J#, Jiang M, Tian S, Liu S, Zhang L*#, Wu S*#, Kan H*#, Gao X*#. Short-term PM2.5 exposure and DNA methylation changes of circadian rhythm genes: Evidence from two experimental studies. Environmental Science & Technology, 2024; 58 (23), 9991–10000. doi: 10.1021/acs.est.4c00108.

2. Jiang M, Tian S, Liu S, Wang Y, Guo X, Huang T, Lin X, Belsky D, Baccarelli AA, Gao X*. Accelerated biological aging elevates the risk of cardiometabolic multimorbidity and mortality. Nature Cardiovascular Research, 2024. doi: 10.1038/s44161-024-00438-8. (專題報道)

3. Gao X*, Tian S, Huang N, Sun G, Huang T. Associations of daily sedentary behavior, physical activity, and sleep with irritable bowel syndrome: a prospective analysis of 362,193 participants. Journal of Sport and Health Science. 2024; 13 (1), 72-80. doi: 10.1016/j.jshs.2023.02.002. (ESI高被引)

4. Gao X*, Tong G, Jiang M, Huang N, Zheng Y, Belsky D*, Huang T. Accelerated biological aging and risk of depression and anxiety: evidence from 424,299 UK Biobank participants. Nature Communications, 2023, doi: 10.1038/s41467-023-38013-7. (ESI高被引)

5. Gao X*, Jiang M, Huang N, Guo X, Huang T. Long-Term Air Pollution, Genetic Susceptibility, and the Risk of Depression and Anxiety: A Prospective Study in the UK Biobank Cohort. Environmental Health Perspectives, 2023, doi: 10.1289/EHP10391. (ESI高被引)

6. Gao X#, Huang J#, Cardenas A, Zhao Y, Sun Y, Wang J, Xue L, Baccarelli AA, Guo X, Zhang L, Wu S. Short-Term Exposure of PM2.5 and Epigenetic Aging: A Quasi-Experimental Study. Environmental Science & Technology, 2022, doi: 10.1021/acs.est.2c05534.

7. Gao X*, Coull B, Lin X, Vokonas P, Spiro A III, Hou L, Schwartz J, Baccarelli AA. Short-term air pollution, cognitive performance and nonsteroidal anti-inflammatory drug use in the Veterans Affairs Normative Aging Study. Nature Aging. 2021; 1(5):430-437. doi:10.1038/s43587-021-00060-4. （封面文章）

8. Gao X*, Coull B, Lin X, Vokonas P, Sparrow D, Hou L, DeMeo D, Litonjua A, Schwartz J, Baccarelli AA. Association of Neutrophil to Lymphocyte Ratio with Reduced Pulmonary Function in a 30-Year Longitudinal Study of US Veterans. JAMA Network Open. 2020; 3:e2010350.

9. Gao X*, Coull B, Lin X, Vokonas P, Schwartz J, Baccarelli AA. Nonsteroidal anti-inflammatory drugs modify the effect of short-term air pollution on lung function. American Journal of Respiratory and Critical Care Medicine. 2020; 201(3):374-8.

10. Gao X, Gào X, Zhang Y, Holleczek B, Schöttker B, Brenner H*. Oxidative stress and epigenetic mortality risk score: associations with all-cause mortality among elderly people. European Journal of Epidemiology. 2019; 451-462.